The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 21, 1998

Filed:

Jun. 07, 1995
Applicant:
Inventors:

Carl R Illig, Phoenixville, PA (US);

Richard M Soll, Lawrenceville, NJ (US);

Joseph M Salvino, Schwenksville, PA (US);

Bruce E Tomczuk, Collegeville, PA (US);

Tianbao Lu, Exton, PA (US);

Nalin L Subasinghe, West Chester, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514602 ; 514305 ; 514357 ; 514535 ; 514603 ; 514604 ; 564 84 ; 564 86 ; 564 90 ; 564 91 ; 560 10 ; 560 13 ; 562429 ; 562430 ; 546133 ; 546334 ;
Abstract

The present invention is directed to non-peptidic factor Xa inhibitors which are useful for the treatment of arterial and venous thrombotic occlusive disorders, inflammation, cancer, and neurodegenerative diseases. The factor Xa inhibitors provide compounds of structure: ##STR1## or pharmaceutically acceptable salts thereof; wherein


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