The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 24, 1998
Filed:
Jun. 07, 1995
Applicant:
Inventors:
Maninder Singh Hora, Rodeo, CA (US);
Joseph Rubinfeld, Danville, CA (US);
Warren Stern, Gainesville, FL (US);
Gregory J Wong, San Leandro, CA (US);
Assignee:
Chiron Corporation, Emeryville, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
424 851 ; 424 852 ; 424 854 ; 424 856 ; 424 943 ; 514-2 ; 514-3 ; 514 12 ; 514 21 ;
Abstract
The invention provides a method for the solubilization and/or stabilization of polypeptides, especially proteins, using a cyclodextrin selected from the group consisting of hydroxypropyl, hydroxyethyl, glucosyl, maltosyl and maltotriosyl derivatives of .beta.- and .gamma.-cyclodextrin. Solubilized and/or stabilized compositions comprising a polypeptide, especially a protein, and the selected cyclodextrin are also described.