The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 1998
Filed:
Jun. 05, 1995
Applicant:
Inventors:
Jeffrey P Knittel, Ames, IA (US);
Michael B Roof, Ames, IA (US);
Assignee:
NOBL Laboratories, Inc., Ames, IA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; A61K / ;
U.S. Cl.
CPC ...
4352521 ; 435245 ; 435366 ; 435383 ; 435395 ; 435403 ; 424 933 ; 424 934 ; 4242341 ;
Abstract
A method for large scale cultivation and attenuation of IS intracellularis bacteria by inoculating cells with IS intracellularis bacteria to infect the cells, incubating the infected cells in a reduced oxygen concentration and maintaining the infected cells in suspension. Anti-IS intracellularis vaccines are prepared from attenuated strains. Diagnostic agents are also disclosed.