The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 30, 1997

Filed:

Jun. 07, 1995
Applicant:
Inventors:

Joseph Edward Semple, San Diego, CA (US);

Robert John Ardecky, Encinitas, CA (US);

Ruth Foelsche Nutt, San Diego, CA (US);

William Charles Ripka, San Diego, CA (US);

David C Rowley, Encinitas, CA (US);

Marguerita S Lim-Wilby, La Jolla, CA (US);

Terence Kevin Brunck, San Diego, CA (US);

Assignee:

Corvas International, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07F / ;
U.S. Cl.
CPC ...
530331 ; 540463 ; 540487 ; 540524 ; 540527 ; 546 24 ; 546192 ; 546243 ; 548413 ; 548517 ; 548547 ; 514 18 ; 514 19 ; 514 20 ;
Abstract

The present invention discloses peptide aldehydes which are potent and specific inhibitors of thrombin, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.


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