The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 1997
Filed:
Jun. 07, 1995
Applicant:
Inventors:
Stephen D Wolpe, Arlington, MA (US);
Anthony Cerami, Shelter Island, NY (US);
Assignee:
The Rockefeller University, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
435 7021 ; 435335 ; 435326 ; 435340 ; 435346 ; 53038823 ; 5303884 ; 5303871 ;
Abstract
The present invention pertains to the novel hybridoma SDW18.1.1, hybridomas obtained from SDW18.1.1, monoclonal antibodies obtained from such hybridomas and derivatives of such monoclonal antibodies. The novel hybridomas are formed by fusion of cells from a mouse myeloma line and spleen cells from a mouse previously immunized with cachectin/TNF. Diagnostic and therapeutic utilities for the monoclonal antibodies and their derivatives are proposed, and testing procedures, materials in kit form and pharmaceutical compositions are likewise set forth.