The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 16, 1997
Filed:
Dec. 16, 1994
Phillip Dan Cook, San Marcos, CA (US);
David J Ecker, Leucadia, CA (US);
Jacqueline Wyatt, Carlsbad, CA (US);
Thomas W Bruice, Carlsbad, CA (US);
Kevin Anderson, Carlsbad, CA (US);
Ronnie Hanecak, San Clemente, CA (US);
Timothy Vickers, Oceanside, CA (US);
Peter Davis, Carlsbad, CA (US);
Susan M Freier, San Diego, CA (US);
Yogesh S Sanghvi, San Marcos, CA (US);
Vickie Brown-Driver, San Diego, CA (US);
ISIS Pharmaceuticals, Inc., Carlsbad, CA (US);
Abstract
Methods useful for the determination of oligomers which have specific activity for a target molecule from a pool of primarily randomly assembled oligomers are provided. The disclosed methods involve repeated syntheses of increasingly simplified sets of oligomers coupled with selection procedures for determining oligomers having the highest activity. Freedom from the use of enzymes allows the application of these methods to any molecules which can be oligomerized in a controlled fashion.