The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 21, 1997
Filed:
Oct. 27, 1994
Eitan Friedman, Wynnewood, PA (US);
M Katharine Holloway, Lansdale, PA (US);
Gideon A Rodan, Bryn Mawr, PA (US);
Su Jane Rutledge, East Greenville, PA (US);
Azriel Schmidt, Bryn Mawr, PA (US);
Robert L Vogel, Richboro, PA (US);
Merck & Co., Inc., Rahway, NJ (US);
Medical College of Pennsylvania, Philadelphia, PA (US);
Hahnemann Univ., Philadelphia, PA (US);
Abstract
The NER receptor is a novel member of the steroid hormone receptor superfamily and has been prepared by cDNA cloning from a human osteosarcoma SAOS-2/B10 cell library. The complete sequence of human NER complementary DNA (Seq. ID No. 1), expression systems including a COS stable expression system, the expressed protein (SEQ. ID No. 2) and an assay using the COS expression system are disclosed. The assay may be used to identify agents which activate transcription mediated by the NER receptor, and which are useful for potentiating the activity of a modulator of a G-protein coupled receptor wherein the G-protein coupled receptor is a member of the steroid hormone receptor superfamily.