The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 1997
Filed:
Nov. 04, 1994
Applicant:
Inventors:
Bernard F Spielvogel, Raleigh, NC (US);
Anup Sood, Durham, NC (US);
Iris H Hall, Carrboro, NC (US);
Barbara Ramsay Shaw, Durham, NC (US);
Jeno Tomasz, Durham, NC (US);
Assignees:
University of North Carolina, Chapel Hill, NC (US);
Boron Biologicals, Inc., Raleigh, NC (US);
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ;
U.S. Cl.
CPC ...
536 267 ; 536-41 ; 536 171 ; 536 221 ; 536 2671 ; 536 268 ; 536 271 ; 536 2721 ; 536 274 ; 536 276 ; 536 2763 ; 536 278 ; 536 2781 ; 536 281 ; 536 285 ; 536 2853 ; 536 2854 ;
Abstract
A novel class of pharmaceutically active boronated compounds are provided. The boronated compounds include boronated purine and pyrimidine bases and boronated nucleosides, as well as phosphate esters and oligomers thereof. The compounds are boronated at the ring nitrogen of the purine or pyrimidine base, or at a 2', 3' or 5' amino substituent of the nucleoside sugar.