The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 1997
Filed:
Jan. 05, 1995
Applicant:
Inventors:
Kent Alan Berryman, Ann Arbor, MI (US);
Xue-Min Cheng, Ann Arbor, MI (US);
Annette Marian Doherty, Ann Arbor, MI (US);
Jeremy John Edmunds, Ypsilanti, MI (US);
Sylvester Klutchko, Ann Arbor, MI (US);
Assignee:
Warner-Lambert Company, Morris Plains, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
514466 ; 514538 ; 514539 ; 514562 ; 514563 ; 514567 ; 514 63 ; 514617 ; 514464 ; 560 40 ; 562439 ; 562446 ; 549435 ; 549444 ; 556419 ;
Abstract
Novel antagonists of endothelin are described, as well as novel intermediates used in their preparation, methods for the preparation and pharmaceutical compositions of the same, which are useful in treating elevated levels of endothelin, essential, renovascular, malignant and pulmonary hypertension, cerebral infarction, myocardial ischemia, cerebral ischemia, congestire heart failure and subarachnoid hemorrhage.