The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 1997
Filed:
Feb. 20, 1996
Vitaly Arkadievich Livshits, Moscow, RU;
Vladimir Georgievich Debabov, Moscow, RU;
Aaveilova Oksaua Fedorovva, Moscow, RU;
Zakataeva Natalya Pavlovva, Moscow, RU;
Rustem Saidovich Shakulov, Moscow, RU;
Tatyana Alexandrovna Bachina, Moscow, RU;
Evgeny Moiseevich Khurges, Moscow, RU;
Ajinomoto Co., Inc., Tokyo, JP;
Abstract
A method for constructing microorganism strains which produce amino acids comprising: combining in one bacterial genome (a) a mutation affecting the aminoacyl-tRNA synthetase corresponding to the selected amino acid, conferring cells auxotrophy which cannot be fully suppressed by addition of usual concentration this amino acid into the culture medium and (b) a mutation which destroys the negative regulation of selected amino acid biosynthesis to yield a strain capable of increased production of the selected amino acid. Strains producing isoleucine and valine. Methods to produce isoleucine and valine by culturing those strains.