The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 1997
Filed:
Jan. 31, 1992
Applicant:
Inventors:
Nassim Usman, Boston, MA (US);
Robert J Cedergren, Montreal, CA;
Jean-Pierre Perreault, Rawdon, CA;
Jing-Hua Yang, Montreal, CA;
Alexander Rich, Cambridge, MA (US);
Assignees:
University of Montreal, Montreal, CA;
Massachusetts Institute of Technology, , MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12N / ;
U.S. Cl.
CPC ...
435-6 ; 435 9131 ; 4351721 ; 4351723 ; 536 231 ; 536 232 ; 536 245 ; 514 44 ;
Abstract
Nucleozymes containing ribonucleotides and deoxyribonucleotides or nucleic acid analogues are described herein. The nucleozymes have catalytic activity and are significantly more resistant to degradation than their all-RNA ribozyme counterparts. Also described are methods for preparing the nucleozymes along with methods of using nucleozymes, e.g., as therapeutic agents.