The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 15, 1997
Filed:
Mar. 07, 1991
Applicant:
Inventors:
Scott Buttram, Downingtown, PA (US);
Richard T Dean, Downingtown, PA (US);
John Lister-James, Glenmoore, PA (US);
Koon Yan Pak, Norristown, PA (US);
Assignee:
Centocor, Inc., Malvern, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ;
U.S. Cl.
CPC ...
424-149 ; 5303915 ;
Abstract
A one vial method for labeling a sulfhydryl containing antibody or antibody fragment with technetium-99m is disclosed. The method comprises contacting an antibody mixture comprised of a sulfhydryl containing antibody or antibody fragment and a reducing agent with technetium-99m in an oxidized state. In a preferred embodiment, the antibody mixture further contains a water soluble ligand. A one vial kit for labeling a sulfhydryl containing antibody or antibody fragment with technetium-99m is also disclosed.