The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 1997

Filed:

Jun. 07, 1995
Applicant:
Inventors:

Graham S Poindexter, Old Saybrook, CT (US);

Marc Bruce, Wallingford, CT (US);

Graham Johnson, Madison, CT (US);

Michael Kozlowski, Palo Alto, CA (US);

Karen LeBoulluec, Wallingford, CT (US);

Ivo Monkovic, Durham, CT (US);

Ramakrishna Seethala, Cranbury, NJ (US);

Charles P Sloan, Wallingford, CT (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514218 ; 514252 ; 540575 ; 544364 ; 544365 ;
Abstract

A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of piperazine and homopiperazine derivatives of 4-phenyl-1,4-dihydropyridines of Formula (I). ##STR1## As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.


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