The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 28, 1997

Filed:

Apr. 28, 1994
Applicant:
Inventors:

Dennis M Brown, Menlo Park, CA (US);

Edward Luck, Menlo Park, CA (US);

Daniel R Twardzik, Bainbridge Island, WA (US);

Anthony F Purchio, Seattle, WA (US);

Assignees:

Oncogen, , WA (US);

Matrix Pharmaceuticals, , CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
424422 ; 424423 ; 424426 ; 424484 ; 514 12 ; 514 21 ; 530350 ; 530356 ; 530399 ;
Abstract

Antiproliferative compositions are provided which are capable of sustained release of an antiproliferative agent, particularly a TGF-.beta., at a site proximal to a target cell. The compositions are effective in inhibiting proliferation of the target cell, particularly when used in combination with a vasoconstrictive agent.


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