The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 1997
Filed:
Dec. 03, 1993
Applicant:
Inventors:
Barbara Chapman, Berkeley, CA (US);
Rae L Burke, San Francisco, CA (US);
Assignee:
Chiron Corporation, Emeryville, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 696 ; 4352402 ; 4353201 ; 530383 ; 536 235 ; 536 242 ;
Abstract
DNA constructs encoding human Factor VIII:C protein are disclosed. In particular, the DNA construct contains a nucleotide sequence that encodes a first polypeptide homologous to the A domain of human Factor VIII:C linked to a second polypeptide homologous to the C domain of human Factor VIII:C by a polypeptide spacer that comprises a peptide homologous to a human Ig heavy chain hinge region. Recombinant methods for producing human Factor VIII:C protein are also disclosed.