The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 28, 1996
Filed:
May. 05, 1994
Applicant:
Inventor:
Gary D Madding, Evansville, IN (US);
Assignee:
Bristol-Myers Squibb Company, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
544230 ; 544231 ; 544295 ;
Abstract
An improved process for preparation of certain useful azapirones, e.g. buspirone, gepirone, tandospirone, etc., comprises the reaction of a novel spiroquaternary piperazinium hydroxide with an appropriate imide to form imidate salts which are then converted to the azapirone by heating. This process is suitable for large scale adaptation and has advantages in greater safety and efficiency.