The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 14, 1996
Filed:
Aug. 22, 1994
Applicant:
Inventor:
Steven M Reppert, Newton, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; F12N / ;
U.S. Cl.
CPC ...
530350 ; 435 691 ; 536 235 ;
Abstract
Disclosed are cDNAs encoding A.sub.2b -adenosine receptors and the recombinant proteins expressed from such cDNAs. The recombinant receptor and receptor fragments and analogs are used in methods of screening candidate compounds for their ability to antagonize interaction between adenosine and an A.sub.2b -adenosine receptor; antagonists are used as therapeutics to reduce inflammatory gastrointestinal tract diseases or asthma. Antibodies specific for A.sub.2b -adenosine receptor (or receptor fragment or analog) and their use as a therapeutic and diagnostic are also disclosed.