The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 1995

Filed:

Apr. 20, 1992
Applicant:
Inventors:

John G Atwood, West Redding, CT (US);

Albert C Mossa, Trumbull, CT (US);

Lisa M Goven, Bridgeport, CT (US);

Fenton Williams, Brookfield, CT (US);

Timothy M Woudenberg, Bethel, CT (US);

Marcel Margoulies, Scarsdale, NY (US);

Robert P Ragusa, Newton, CT (US);

Richard Leath, Berkley, CA (US);

Clive Miles, San Rafael, CA (US);

Assignee:

The Perkin-Elmer Corporation, Norwalk, CT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G06G / ;
U.S. Cl.
CPC ...
364500 ; 364496 ; 364497 ; 364498 ; 364499 ; 165 12 ;
Abstract

An instrument for performing highly accurate PCR employing a sample block in microtiter tray format. The sample block has local balance and local symmetry. A three zone film heater controlled by a computer and ramp cooling solenoid valves also controlled by the computer for gating coolant flow through the block controls the block temperature. Constant bias cooling is used for small changes. Sample temperature is calculated instead of measured. A platen deforms plastic caps to apply a minimum acceptable threshold force for seating the tubes and thermally isolates them. A cover isolates the block. The control software includes diagnostics. An install program tests and characterizes the instrument. A new user interface is used. Disposable, multipiece plastic microtiter trays to give individual freedom to sample tubes are taught.

Published as:
CA2056743A1; CA2266010A1; CA2395941A1; CA2436618A1; EP0488769A2; IE914170A1; AU8832791A; DE488769T1; GR920300125T1; ES2033640T1; EP0488769A3; JPH06233670A; IL100209A; AU662494B2; NZ240800A; NZ270628A; NZ270629A; AU2493495A; US5475610A; IL111091A; IL111092A; US5602756A; EP0810030A1; EP0812621A1; US5710381A; EP0488769B1; ATE165621T1; DE69129325D1; DE812621T1; AU696482B2; DE69129325T2; DE810030T1; DK0488769T3; CA2056743C; KR100236506B1; US6015534A; EP1157744A1; EP0812621B1; ATE216284T1; DE69132992D1; CA2266010C; EP1275438A2; DE69132992T2; EP0810030B1; ATE233600T1; EP1275438A3; DE69133211D1; DK0810030T3; DE1157744T1; DE1275438T1; DE69133211T2; EP1157744B1; ATE261774T1; DE69133376D1; EP1452608A1; JP2004313203A; JP2004321192A; DE69133376T2; EP1510823A2; EP1510823A3; IE20050462A1; IE20020984A1; JP2006223312A; CA2395941C; JP2006262903A; EP1452608B1; ATE373107T1; CA2436618C; DE69133579D1; DK1452608T3; ES2293111T3; EP0810030B2; DE69133579T2; DK0810030T4; EP1967857A2; EP1510823B1; DE69133211T3; ATE409315T1; IE20080750A1; DE69133605D1; DK1510823T3; EP1967857A3; ES2318232T3; JP2009207501A; JP2011019537A; JP4795089B2;

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