The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 1995

Filed:

Jul. 27, 1992
Applicant:
Inventors:

Roman Vetter, Burgdorf, DE;

Ingo Muecke, Barsinghausen, DE;

Detlef Wilke, Wennigsen, DE;

Amory Antoine, Rixensart, BE;

Wolfgang Aehle, Delft, NL;

Harald Sobek, Ummendorf, DE;

Dietmar Schomburg, Braunschwig, DE;

Andre Clippe, Walhain, BE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435222 ; 435221 ; 435219 ;
Abstract

Enzymes stabilized against the destabilizing effect of ionic surfactants and a method of producing such stabilized enzymes in which DNA sequences which code for the enzymes are modified by directed mutation in defined positions which correlate with defined surface regions of the enzyme, in such a way that the codon in which the mutation is located now codes for an amino acid differing from the original amino acid.


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