The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 1994
Filed:
Jul. 07, 1992
Applicant:
Inventors:
Bernard F Spielvogel, Raleigh, NC (US);
Anup Sood, Durham, NC (US);
Iris H Hall, Carrboro, NC (US);
Barbara R Shaw, Durham, NC (US);
Jeno Tomasz, Durham, NC (US);
Assignees:
University of North Carolina at Chapel Hill, Chapel Hill, NC (US);
Boron Biologicals, Raleigh, NC (US);
Duke Unversity, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514256 ; 514261 ; 514269 ; 514824 ; 514825 ; 514886 ; 544242 ; 544264 ;
Abstract
A novel class of pharmaceutically active boronated compounds are provided. The boronated compounds include boronated purine and pyrimidine bases and boronated nucleosides, as well as phosphate esters and oligomers thereof. The compounds are boronated at the ring nitrogen of the purine or pyrimidine base, or at a 2', 3' or 5' amino substituent of the nucleoside sugar.