The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 08, 1994
Filed:
Mar. 31, 1992
Applicant:
Inventors:
Bert Vogelstein, Baltimore, MD (US);
Kenneth W Kinzler, Baltimore, MD (US);
Michael I Sherman, Glen Ridge, NJ (US);
Assignees:
The John Hopkins University, Baltimore, MD (US);
PharmaGenics, Inc., Allendale, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q / ;
U.S. Cl.
CPC ...
435-6 ; 4353201 ; 536 241 ; 536 2431 ; 424-2 ;
Abstract
Specific sequences in the human genome are the sites of strong binding of wild-type p53 protein, but not mutant forms of the protein. These sequences are used diagnostically to detect cells in which the amount of wild-type p53 is diminished. The sequences can also be used to screen for agents which correct for loss of wild-type p53 to DNA in cancer cells.
Quick Actions:
Vogelstein, Bert. (1994). Sequence specific dna binding by p53 (U.S. Patent No. 5362623). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5362623
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile