logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5352769 B1

PDFFull Text
Date of Patent:
Oct. 04, 1994

Filed:

Apr. 06, 1992

Enzymatic removal of a protein amino-terminal sequence

Applicant:
Inventors:

Gerald W Becker, Indianapolis, IN (US);

Thomas C Furman, Indianapolis, IN (US);

Warren C MacKellar, Indianapolis, IN (US);

James P McDonough, Indianapolis, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorneys:

Maciak; Ronald S.

Cantrell; Paul R.

Primary Examiner:

George C Elliott

Int. Cl.
CPC ...
C07K / ; A61K / ;
U.S. Cl.
CPC ...
530303 ; 530305 ; 435 681 ;
Abstract

This disclosure relates to new compounds and to a process for the controlled conversion of such compounds to produce a Protein that comprises an amino acid sequence which is useful as a precursor to human insulin or to a modified human insulin, the amino terminus portion of which sequence does not define a cathepsin C dipeptide removal stop point. The compounds have the formula Met-Y-Protein in which Y is Tyr or Arg.

Find Patent Forward Citations

Becker, Gerald. (1994). Enzymatic removal of a protein amino-terminal sequence (U.S. Patent No. 5352769). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5352769

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…