The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 06, 1994

Filed:

Dec. 10, 1992
Applicant:
Inventors:

Sander G Mills, Woodbridge, NJ (US);

Richard J Budhu, Monmouth Junction, NJ (US);

Conrad P Dorn, Plainfield, NJ (US);

William J Greenlee, Teaneck, NJ (US);

Malcolm MacCoss, Freehold, NJ (US);

Mu T Wu, Clark, NJ (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
5142358 ; 5142278 ; 5142282 ; 5142325 ; 514253 ; 514255 ; 514252 ; 544 60 ; 544121 ; 544357 ; 544360 ; 544361 ; 544372 ; 544387 ; 544388 ; 544336 ; 544390 ; 558390 ; 560 25 ; 560157 ;
Abstract

Diacylpiperazines of general structure ##STR1## are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, and asthma, and calcium channel blockers useful in the treatment of cardiovascular conditions such as angina, hypertension or ischemia.


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