The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 1994
Filed:
Dec. 06, 1991
Steven A Krilis, Hunter's Hill, AU;
Hugh P McNeill, Jannali, AU;
Colin N Chesterman, Bellevue Hill, AU;
Abstract
A method for determining whether antiphospholipid antibodies are present in a sample is disclosed. The method comprises contacting the sample with a negatively charged phospholipid and with .beta.-2-glycoprotein-I or a homolog or analog thereof and determining whether any antiphospholipid antibodies have bound to the contacted phospholipid and .beta.-2-glycoprotein-I, wherein detection of binding of antiphospholipid antibodies to the phospholipid and .beta.-2-glycoprotein-I, is indicative that antiphospholipid antibodies are present in the sample. Also disclosed is a method for determining whether a negatively charged phospholipid is present in a sample, a kit for use in an assay for determining whether antiphospholipid antibodies are present in a sample, a kit for use in an assay for determining whether a negatively charged phospholipid is present in a sample, a method for determining whether antiphospholipid antibodies in a sample are antibodies to an autoimmune disease or antibodies to an infectious disease and a method for determining whether antiphospholipid antibodies to an autoimmune disease and antiphospholipid antibodies to an infectious disease are present in a sample.