The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 26, 1994
Filed:
Jun. 30, 1993
Hiroshi Yoshino, Chiba, JP;
Norihiro Ueda, Ibaraki, JP;
Hiroyuki Sugumi, Ibaraki, JP;
Jun Niijima, Ibaraki, JP;
Yoshihiko Kotake, Ibaraki, JP;
Toshimi Okada, Ibaraki, JP;
Nozomu Koyanagi, Ibaraki, JP;
Tatsuo Watanabe, Osaka, JP;
Makoto Asada, Ibaraki, JP;
Kentaro Yoshimatsu, Ibaraki, JP;
Atsumi Iijima, Ibaraki, JP;
Takeshi Nagasu, Ibaraki, JP;
Kappei Tsukahara, Ibaraki, JP;
Kyosuke Kitoh, Ibaraki, JP;
Eisai Co., Ltd., Tokyo, JP;
Abstract
Sulfonamide derivatives of the general formula (I): ##STR1## wherein preferably R.sup.1 represents a lower alkoxy group, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 may be the same or different from one another and each represent a hydrogen atom, halogen atom or lower alkyl group, A and B may be the same or different from each other and each represent .dbd.N-- or .dbd.CH--, E represents an aromatic 6-membered cyclic group, which may have 1 or 2 nitrogen atoms in the ring, and be substituted with 1 to 3 substituents which may be the same or different from one another with the proviso that a combination of R.sup.1 which is a hydrogen atom, lower alkyl group, nitro group or amino group which may be protected, R.sup.2 and R.sup.3 which are each a hydrogen atom, A and B which are each .dbd.CH-- and E which is a phenyl group which may be substituted with 1 to 3 substituents G which may be the same or different from one another is excluded, or pharmacologically acceptable salts of them, have an excellent antitumor activity.