The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 03, 1994
Filed:
Nov. 19, 1992
Applicant:
Inventors:
John C Hodges, Ann Arbor, MI (US);
Sylvester Klutchko, Ann Arbor, MI (US);
Assignee:
Warner-Lambert Company, Morris Plains, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514336 ; 514341 ; 514365 ; 514374 ; 514378 ; 514381 ; 514397 ; 546246 ; 548189 ; 548240 ; 548253 ; 5483144 ;
Abstract
Substituted 1-benzylimidazole-5-methylidene hydantoins are disclosed as well as methods of preparing them, pharmaceutical compositions containing them, and method of using them. Intermediates useful in the preparation of the compounds of the invention are also disclosed and synthetic methods for preparing the novel intermediates. The compounds are useful as antagonists of angiotensin II and thus are useful in the control of hypertension, hyperaldosteronism, congestive heart failure, surgically induced vascular smooth muscle proliferation, and glaucoma.