The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 1994
Filed:
Sep. 13, 1991
Applicant:
Inventors:
Armelle Delecluse, Thiers Sur Theve, FR;
Andre Klier, Neuilly S/Marne, FR;
Georges Rapoport, Paris, FR;
Assignee:
Institut Pasteur, Paris, FR;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
43525231 ; 435 691 ; 435 712 ; 4351721 ; 4351723 ; 4352523 ; 4352525 ; 4353201 ; 435832 ; 536 2371 ; 935 10 ; 935 29 ; 935 56 ; 935 74 ; 514-2 ;
Abstract
The cyta gene encoding the 28 kDa polypeptide of Bacillus thuringiensis israelensis crystals was disrupted in the 72 MDa resident plasmid by in vivo recombination. The absence of the 28 kDa protein in B. thuringiensis israelensis did not affect the crystallization of the other toxic components of the parasporal body. However, the absence of the 28 kDa protein did abolish the hemolytic activity of B. thuringiensis serovar israelensis crystals. The mosquitocidal activity of the 28 kDa protein-free crystals did not differ significantly from the wild-type crystals.