The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 12, 1994
Filed:
Oct. 06, 1992
Applicant:
Inventors:
Kevin M Byrne, West Trenton, NJ (US);
Shieh-Shung T Chen, Morganville, NJ (US);
Louis Kaplan, New City, NY (US);
John G MacConnell, Westfield, NJ (US);
Brian R Petuch, Florence, NJ (US);
Raymond F White, Palmyia, VA (US);
Byron H Arison, Watchung, NJ (US);
Assignee:
Merck & Co., Inc., Rahway, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
514338 ; 514397 ; 514444 ; 514452 ; 514414 ; 546270 ; 5483117 ; 548463 ; 549 60 ; 549363 ;
Abstract
Compounds of Structural Formula (I) ##STR1## are produced by directed biosynthesis. These compounds are squalene synthetase inhibitors and thus useful as cholesterol lowering agents, antifungal agents and cancer treatment agents.