The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 01, 1994
Filed:
Jun. 15, 1992
Toshihiko Terao, Nagoya, JP;
Naohiro Kanayama, Hamamatsu, JP;
Akihiro Morioka, Nagoya, JP;
Yoshika Yasuda, Nagoya, JP;
Masami Kamiya, Nagoya, JP;
Juichi Awaya, Nagoya, JP;
Masayasu Kurono, Nagoya, JP;
Kiichi Sawai, Nagoya, JP;
Sanwa Kagaku Kenkyusho Co., Ltd., Nagoya, JP;
Abstract
Even when the specimen contains human granulocyte elastase in the form of a mixture of free elastase with an elastase-inhibitor complex or complexes, the present invention enables the total quantity of elastase in that specimen to be precisely detected. The inhibitor is added to free elastase to convert it into an elastase-inhibitor complex, whereby the quantity of elastase can be measured by immunoassay as the total amount including the previously existing elastase-inhibitor complex. It is possible to precisely measure the total amount of elastase in mucus collected from the cervical canal of a pregnant woman, sputum or a rinsed solution of bronchovesicular lavage in which free elastase is mixed with an elastase-inhibitor complex. It is thus possible to predict and prevent threatened premature delivery, premature delivery or premature rupture of membranes by immunoassay of mucus collected from the cervical canal of a pregnant woman, to make a diagnosis of chronic or repetitive airway infections and pulmonary emphysema based on chronic respiratory diseases by immunoassay of sputum and a rinsed solution of bronchovesicular lavage and to make a diagnosis of urinary tract infections by immunoassay of urine.