The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 15, 1994
Filed:
Apr. 12, 1990
Applicant:
Inventors:
Philippe Bey, Cincinnati, OH (US);
James K Coward, Ann Arbor, MI (US);
John J McGuire, Kenmore, NY (US);
Assignees:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Health Research, Inc., Buffalo, NY (US);
Merrell Dow Pharmaceuticals Inc., Cincinnati, OH (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514249 ; 514258 ; 514259 ; 514260 ; 544258 ; 544259 ; 544260 ; 544279 ; 544287 ; 544291 ; 544292 ;
Abstract
This invention relates to certain conjugates of folates and antifolates with difluoroglutamic acid which are useful in the treatment of patients suffering from certain neoplastic diseases including leukemia, melanomas, carcinomas, sarcomas and mixed neoplasias.