The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 1993
Filed:
Jan. 17, 1992
Applicant:
Inventors:
Randal J Kaufman, Boston, MA (US);
S Robert Adamson, Chelmsford, MA (US);
Assignee:
Genetics Institute, Inc., Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ;
U.S. Cl.
CPC ...
435 696 ; 435 691 ; 4351723 ; 4353201 ; 4352402 ; 4352403 ; 43524031 ; 930100 ; 935 33 ; 935 34 ; 935 60 ; 935 70 ;
Abstract
An improved method for producing Factor VIII:c-type proteins is disclosed which involves culturing mammalian cells which are capable of expressing the protein. In accordance with this invention the cells are cultured in a medium containing an effective amount of a substance comprising (a) von Willebrand Factor-type protein, (b) a phospholipid or phospholipid mixture, or a mixture of (a) and (b).