The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 1993
Filed:
Jul. 18, 1988
Applicant:
Inventors:
Raymond Baker, Much Hadham, GB;
John Saunders, Bishop's Stortford, GB;
Angus M MaCleod, Bishop's Stortford, GB;
Graham A Showell, Welwyn Garden City, GB;
Assignee:
Merck Sharp & Dohme Limited, Hoddesdon, GB;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514299 ; 514304 ; 514305 ; 514340 ; 514364 ; 546112 ; 546125 ; 546133 ; 546137 ; 546277 ; 548133 ;
Abstract
A class of novel oxadiazoles, substituted on one of the ring carbon atoms with a non-aromatic azacyclic or azabicyclic ring and on the other ring carbon atom with a substituent which is convertible in vivo to an amino group, are potent muscarinic agonists, and exhibit improved CNS penetrability and duration of action compared with the corresponding amino compounds. The compounds are therefore useful in the treatment of neurological and mental illnesses.