The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 1993
Filed:
Jan. 10, 1992
Shieh-Shung T Chen, Morganville, NJ (US);
Raymond F White, Englishtown, NJ (US);
Georgette Dezeny, Short Hills, NJ (US);
Brian R Petuch, Florence, NJ (US);
George M Garrity, Westfield, NJ (US);
Byron H Arison, Watchung, NJ (US);
Amy M Bernick, Glen Gardner, NJ (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
Described is a process for producing a new immunosuppressant, a C-19/C-22 cyclic hemiketal (Compound I) biotransformation analog of FR-900520, under novel fermentation conditions utilizing the novel microorganism, Streptomyces sp. (Merck Culture Collection MA6963) ATCC No. 55230. The macrolide immunosuppressant is useful in preventing human host rejection of foreign organ transplants, e.g. bone marrow, liver, lung, kidney and heart transplants.