The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 23, 1993
Filed:
May. 19, 1989
Applicant:
Inventor:
Amy S Lee, San Marino, CA (US);
Assignee:
The University of Southern California, University Park, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ;
U.S. Cl.
CPC ...
536 235 ; 435 691 ; 4351723 ; 4353201 ; 935-6 ;
Abstract
The regulatory sequence for a glucose regulated protein has been isolated. When fused into suitable expression vectors within reading relationship of a desired polypeptide DNA sequence, the resulting hybrid gene can be induced to high levels by glucose starvation, or calcium shock, or by denaturing reagents such as .beta.-mercaptoethanol, in a variety of host systems. Further, the hybrid gene can also be regulated by temperature when it is introduced into temperature-sensitive host systems such as the temperature-sensitive mutant of Chinese hamster cells or other systems having a compatible mutation.