The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 09, 1993
Filed:
Feb. 27, 1992
Laszlo R Treiber, Gillette, NJ (US);
Lawrence F Colwell, Jr, Eatontown, NJ (US);
Byron H Arison, Watchung, NJ (US);
Georgette Dezeny, Short Hills, NJ (US);
Russell B Lingham, Watchung, NJ (US);
Wayne J Thompson, Lansdale, PA (US);
Suresh K Balani, Hatfield, PA (US);
Merck & Co., Inc., Rahway, NJ (US);
Abstract
A dipeptide isostere is the biotransformed product after incubation with a culture of Streptomyces. It inhibits HIV protease, and is useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as a compound, pharmaceutically acceptable salt, pharmaceutical composition ingredient, whether or not as a prodrug or as a combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.