The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 05, 1993
Filed:
Sep. 16, 1991
Applicant:
Inventors:
Norman E Lloyd, Sparta, NJ (US);
Richard L Antrim, Sparta, NJ (US);
Assignee:
Stabra AG, Zug, CH;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 94 ; 435179 ; 435180 ; 435234 ;
Abstract
This invention provides a method for the maintenance of continuous activity of an immobilized enzyme reaction by initially underloading an adsorbent with a desired enzyme, monitoring the activity of the enzyme and periodically adding fresh enzyme to maintain a constant, continuous level of activity until the maximum carrying capacity of the support is reached. The method is preferably carried out when continuously isomerizing glucose to fructose with glucose isomerase adsorbed to a weakly basic anion exchange resin.