The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 15, 1992

Filed:

Feb. 22, 1990
Applicant:
Inventors:

Thangavel Kuberasampath, Medway, MA (US);

Richard J Ridge, Acton, MA (US);

Assignee:

Stryker Corporation, Kalamazoo, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F / ; C08J / ; C08L / ; C07K / ;
U.S. Cl.
CPC ...
424423 ; 424424 ; 424426 ; 523113 ; 530356 ; 530840 ; 128D / ;
Abstract

A matrix for implantation in a mammalian host comprising biocompatible, mineral-free, insoluble Type-I bone collagen which may be allogenic or xenogenic to the host, and which, when implanted in the host, is biodegradable. The collagen is treated with a collagen fibril modifying substance such as acidified acetonitrile, chloroform, or dichloromethane, or by heating in an aqueous environment to a temperature of 37.degree.-65.degree. C. The treated material undergoes a change in morphology involving a significant increase in its surface area as measured by various methods. Under the scanning electron microscope the material has an 'oyster shell' appearance with many pits and micropores.


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