The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 1992
Filed:
Nov. 21, 1990
Applicant:
Inventors:
Thangavel Kuberasampath, Medway, MA (US);
Richard J Ridge, Acton, MA (US);
Assignee:
Stryker Corporation, Kalamazoo, MI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61F / ; C07K / ; C12P / ;
U.S. Cl.
CPC ...
424423 ; 424424 ; 424426 ; 523113 ; 128D / ;
Abstract
Disclosed is a matrix material for implantation in a mammalian host comprising biocompatible mineral-free type I bone collagen, xenogenic to the host, and biodegradable therewithin. The matrix is manufactured from protein-extracted bone powder treated with certain swelling agents to increase its surface area and porosity. The matrix may be combined with osteogenic protein to induce reliably and reproducibly endochondral bone formation. It also can be used as a surface coat around implantable prosthetic devices to promote cellular ingrowth or as a carrier for sustained release of various therapeutic compositions.