The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 27, 1992
Filed:
Jan. 29, 1990
Applicant:
Inventors:
Gautam Mitra, Kensington, CA (US);
Milton M Mozen, Berkeley, CA (US);
Assignee:
Miles Inc., Elkhart, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
5303881 ; 424 858 ; 424530 ; 435236 ; 514-2 ;
Abstract
Antibodies, including monoclonal antibodies (Mabs), can be made substantially free of infectious viruses by storing them in a liquid state at conditions of pH, temperature and time sufficient to inactive substantially all infectious viruses. Preferred inactivation methods involve use of a pH equal to or less than about 4.0 at a temperature of at least about 5.degree. C. for at least about 16 hours.