The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 03, 1992
Filed:
Jan. 26, 1988
Applicant:
Inventors:
Douglas H Keith, Oakland, CA (US);
Mel N Kronick, Palo Alto, CA (US);
Lincoln J McBride, Redwood City, CA (US);
Norman M Whiteley, San Carlos, CA (US);
Assignee:
Applied Biosystems, Foster City, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12Q / ; C12Q / ; C07H / ;
U.S. Cl.
CPC ...
435 91 ; 435-6 ; 435 35 ; 435810 ; 536 27 ;
Abstract
Termini of restricted double-stranded DNA fragments are modified by ligating the fragments with terminal phosphate-free double-stranded oligonucleotides having a complementary terminus in the presence of a restriction enzyme and a ligase, where joining of the complementary ends results in loss of the restriction enzyme recognition sequence.