The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 1992
Filed:
Sep. 24, 1990
Applicant:
Inventors:
Matthew R Powers, Barto, PA (US);
Raymond D Youssefyeh, Princeton Junction, NJ (US);
William L Studt, Harleysville, PA (US);
Frederick A Golec, Merion, PA (US);
Assignee:
Rhone-Poulenc Rorer Pharmaceuticals Inc., Ft. Washington, PA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07B / ; C07C / ;
U.S. Cl.
CPC ...
546133 ; 544105 ; 546 79 ; 546 80 ; 546 81 ; 546 83 ; 546 89 ; 546 90 ; 546101 ; 546110 ; 546111 ; 546 93 ; 546103 ; 546104 ; 546107 ; 546195 ; 546196 ; 546197 ; 546202 ; 564123 ; 564172 ; 564192 ;
Abstract
This invention is directed to certain dibenzofurancarboxamides and dibenzofurancarboxamide acids and their use as 5HT.sub.3 antagonists having unique CNS, anti-emetic and gastric prokinetic activity void of any significant D.sub.2 receptor binding properties. Further, this invention relates to a process for the synthesis of stereoisomeric compounds having such CNS, anti-emetic and gastric prokinetic activity.