The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 16, 1991
Filed:
May. 02, 1989
Benito Casu, Milan, IT;
Giangiacomo Torri, Milan, IT;
Annamaria Naggi, Legnano, IT;
Marisa Mantovani, Villa Guardia, IT;
Rodolfo Pescador, Milan, IT;
Roberto Porta, Cernobbio, IT;
Giuseppe Prino, Milan, IT;
Crinos Industria Farmacobiologica S.p.A., Villa Guardia, IT;
Abstract
Novel derivatives are disclosed as obtained from chondroitin sulfate, dermatan sulfate and hyaluronic acid, having a molar ratio between sulfate groups and carboxylic groups like that of heparin and furthermore characterized by possessing, as the heparin, the sulfoamino group at the carbon atom at the 6 position of hexosamine. The novel compounds show a very remarkable clearing activity in comparison with the starting mucopolysaccharides, this activity being similar and for some derivatives comparable with that of heparin. Moreover, differently from what normally happens upon sulfating the sulfomucopolysaccharides, the anticoagulating activity of the novel compounds is negligible or anyhow very reduced. The compounds of the present invention find use in the therapy of arteriosclerosis.