The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 09, 1990
Filed:
Nov. 16, 1989
Applicant:
Inventors:
Corey Levenson, Oakland, CA (US);
Chu-an Chang, El Cerrito, CA (US);
Fred T Oakes, Rochester, NY (US);
Assignee:
Cetus Corporation, Emeryville, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12Q / ;
U.S. Cl.
CPC ...
435192 ; 435-6 ; 435-7 ; 435 28 ; 435188 ;
Abstract
Oligonucleotides derivatized to incorporate horseradish peroxidase (HRP) are useful in diagnostic methods and provide significant advantage over radioactively labeled oligonucleotide probes. The HRP-derivatized oligonucleotides can be easily and efficiently prepared by reacting a sulfhydryl containing oligonucleotide with a conjugate of a mal-sac-HNSA ester and HRP under mild and easily controlled reaction conditions.