The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 14, 1990
Filed:
May. 09, 1988
Applicant:
Inventors:
Gautam Mitra, Kensington, CA (US);
Milton M Mozen, Berkeley, CA (US);
Assignee:
Miles Laboratories, Inc., Elkhart, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
530387 ; 424 858 ; 424530 ; 435236 ; 514-2 ;
Abstract
Immune serum globulins (ISG) can be made substantially free of infectious retroviruses by storing the ISG in a liquid state at conditions of pH, temperature and time sufficient to inactivate substantially all infectious retroviruses. Preferred inactivation methods involve use of either of two specified storage conditions: (1) at a pH equal to or less than about 4.25 at a temperature of about 27.degree. C. for at least 3 days, or (2) at a pH equal to or less than about 6.8 at a temperature of about 45.degree. C. for at least about 8 hours.