The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 03, 1990
Filed:
Jun. 16, 1988
Applicant:
Inventors:
Hiroaki Tagawa, Tokyo, JP;
Masamichi Sugimori, Tokyo, JP;
Hirofumi Terasawa, Tokyo, JP;
Akio Ejima, Tokyo, JP;
Satoru Ohsuki, Tokyo, JP;
Assignees:
Daiichi Pharmaceutical Co., Ltd., Tokyo, JP;
Kabushiki Kaisha Yakult Honsha, Tokyo, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ;
U.S. Cl.
CPC ...
540578 ; 540581 ; 544361 ; 544362 ; 544125 ; 546 41 ; 546 48 ; 546 51 ;
Abstract
A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: ##STR1## The compound is prepared from an aminoketone compound and a pyranoindolizine compound through Friedlaender reaction. It has an excellent antitumor activity and a high degree of safety, and can be applied as an antitumor medicine for curing tumors of various kinds.