The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 01, 1990
Filed:
Sep. 28, 1987
Applicant:
Inventors:
Satoshi Shuto, Shizuoka, JP;
Hiromichi Itoh, Shizuoka, JP;
Kiyofumi Fukukawa, Shizuoka, JP;
Masatoshi Tsujino, Shizuoka, JP;
Assignee:
Toyo Jozo Kabushiki Kaisha, Shizouka, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ; C07H / ; C07D / ;
U.S. Cl.
CPC ...
536 27 ; 536 28 ; 536 29 ; 544276 ;
Abstract
Novel nucleoside-phospholipid conjugates of the formula ##STR1## wherein R.sub.1 is C.sub.14-24 long chain aliphatic acyl or C.sub.1-24 aliphatic alkyl and N.sub.s is a nucleoside residue; and pharmacologically acceptable salts thereof are prepared in a one-step reaction by reacting the corresponding nucleoside and glycerophospholipid derivative in the presence of phospholipase D-P.