The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 06, 1990
Filed:
Feb. 08, 1988
Applicant:
Inventors:
Masayasu Kurono, Mie, JP;
Hitoshi Noda, Tajimi, JP;
Tomio Ogasawara, Kasugai, JP;
Hidefumi Yamakawa, Kasugai, JP;
Takafumi Iida, Kasugai, JP;
Kunio Yagi, Aichi, JP;
Assignee:
Kabushiki Kaisha Vitamin Kenkyusyo, Gifu, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61J / ; B01J / ; B32B / ;
U.S. Cl.
CPC ...
424450 ; 4284022 ;
Abstract
Some of antineoplastic agents, for instance, adriamycin and daunorubicin, have a positive charge at physiological pH. Such drugs possess high affinity for binding to steroidal sulfate by means of electrostatic force. The invention utilizes this property to prepare steroidal sulfate liposomes having a net negative charge and encapsulating the antineoplastic agent.