The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 1988
Filed:
Aug. 10, 1987
Wolfgang Leuchtenberger, Bruchkobel, DE;
Christian Wandrey, Julich, DE;
Maria-Regina Kula, Wolfenbuttel, DE;
Degussa Aktiengesellschaft, Frankfurt, DE;
Abstract
.alpha.-Hydroxycarboxylic acids are continuously converted into the corresponding optically active .alpha.- aminocarboxylic acids. The conversion is carried out in a membrane reactor in the presence of nicotinamide-adenine dinucleotide increased in molecular weight by bonding to a water soluble high molecular weight material, a dehydrogenase specific for the .alpha.-hydroxycarboxylic acid, a dehydrogenase specific for the corresponding .alpha.-amino-carboxylic acid and ammonium ions. There is continuously supplied to the membrane reactor an aqueous solution of the .alpha.-hydroxycarboxylic acid to be reacted, a substantially lesser amount of the corresponding .alpha.-ketocarboxy lic acid, and an amount of ammonium ion at least equivalent to the .alpha.-hydroxycarboxylic acid to be reacted. There is maintained over the membrane a difference in pressure 1 and 15 bar. Behind the membrane, there is continuously drawn off a filtrate stream containing the .alpha.-aminocarboxylic acid formed.