The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 1988

Filed:

Mar. 29, 1985
Applicant:
Inventors:

Samuel Broder, Bethesda, MD (US);

Shuzo Matsushita, Rockville, MD (US);

Marjorie Robert-Guroff, Rockville, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; G01N / ; G01N / ; A61K / ;
U.S. Cl.
CPC ...
435-5 ; 435-7 ; 435 68 ; 43524027 ; 4351722 ; 436518 ; 436536 ; 436548 ; 436811 ; 436813 ; 935100 ; 935104 ; 935108 ; 935110 ; 424 86 ; 530387 ; 530389 ; 530826 ; 422 61 ;
Abstract

The present invention is an immortalized B-cell line which produces a human monoclonal antibody IgG-Kk which specifically binds to the envelope antigen of human T-cell leukemia virus Type 1 (HTLV-I). This monoclonal antibody is useful as a diagnostic reagent by binding to the antigen specifically expressed on the surface of HTLV producing cells. Furthermore, this monoclonal antibody is useful as a therapeutic reagent, in combination with complement, for the lysis of HTLV-1 producing cells.


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