The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 12, 1988

Filed:

Sep. 13, 1984
Applicant:
Inventors:

Michael A Eaton, Bledlow, GB;

Michael T Doel, Studley Green, GB;

Norman H Carey, Chinnor, GB;

John C Smith, High Wycombe, GB;

David M Lilley, Downley, GB;

Leslie D Bell, Thame, GB;

Assignee:

G. D. Searle & Co., Skokie, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12P / ; C12P / ; C12P / ; C07H / ;
U.S. Cl.
CPC ...
435320 ; 435 70 ; 435 71 ; 435 91 ; 4351723 ; 435 253 ; 536 27 ; 935 13 ; 935 16 ; 935 17 ; 935 29 ; 935 73 ;
Abstract

A synthetic gene characterised in that it codes for the expression of urogastrone or a sub-unit thereof is disclosed. The production thereof by the assembly and ligation of a number of nucleotide blocks is also disclosed, as are corresponding plasmid recombinants, transformed cells and the production thereof. The expression of urogastrone is further disclosed. Urogastrone is a polypeptide hormore (protein) which may be isolated in small amounts from human urine. It has an application in the treatment of ulcers and in the promotion of wound healing. The present invention provides a more viable commercial production.


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